Selected Publications

Shape-Dependent Kinetics of Halide Vacancy Filling in Organolead Halide Perovskites
T. Okamoto, M. Shahjahan, V. Biju
Adv. Opt. Mater. 2021, 2100355 https://doi.org/10.1002/adom.202100355

State of the Art and Prospects for Halide Perovskite Nanocrystals
A. Dey, J. Ye, A. De, E. Debroye, S. K. Ha, E. Bladt, A. S. Kshirsagar, Z. Wang, J. Yin, Y. Wang, L. N. Quan, F. Yan, M. Gao, X. Li, J. Shamsi, T. Debnath, M. Cao, M. A. Scheel, S. Kumar, J. A. Steele, M. Gerhard, L. Chouhan, K. Xu, X. Wu, Y. Li, Y. Zhang, A. Dutta, C. Han, I. Vincon, A. L. Rogach, A. Nag, A. Samanta, B. A. Korgel, C. Shih, D. R. Gamelin, D. H. Son, H. Zeng, H. Zhong, H. Sun, H. V. Demir, I. G. Scheblykin, I. Mora-Seró, J. K. Stolarczyk, J. Z. Zhang, J. Feldmann, J. Hofkens, J. M. Luther, J. Pérez-Prieto, L. Li, L. Manna, M. I. Bodnarchuk, M. V. Kovalenko, M. B. J. Roeffaers, N. Pradhan, O. F. Mohammed, O. M. Bakr, P. Yang, P. Müller-Buschbaum, P. V. Kamat, Q. Bao, Q. Zhang, R. Krahne, R. E. Galian, S. D. Stranks, S. Bals, V. Biju, W. A. Tisdale, Y. Yan, R. L. Z. Hoye,  L. Polavarapu
ACS Nano 2021, 13, doi/10.1021/acsnano.0c08903

Molecular Recognition in the Infection, Replication, and Transmission of COVID-19-Causing SARS-CoV-2: An Emerging Interface of Infectious Disease, Biological Chemistry, and Nanoscience
P. Kumar, J. Sobhanan, Y. Takano,  V. Biju
NPG Asia Mater. 2021, 13, 14, doi.org/10.1038/s41427-020-00275-8

Real-Time Blinking Suppression of Perovskite Quantum Dots by Halide Vacancy Filling
L. Chouhan, S. Ito, E. M. Thomas, Y. Takano, S. Ghimire, H. Miyasaka, V. Biju.
ACS Nano 2021, 10.1021/acsnano.0c08802 (Featured on the cover).

Heterojunction Perovskite Microrods Prepared by Remote‐Controlled Vacancy Filling and Halide Exchange
M. Shahjahan, K. Yuyama, T. Okamoto, V. Biju
Adv. Mater. Technol. 2021, 10.1002/admt.202000934 (Featured on the cover).

A photoanode with plasmonic nanoparticles of earth abundant bismuth for photoelectrochemical reactions
P. Subramanyam, M. Deepa, S. S. K. Raavi, H. Misawa, V. Biju, C. Subrahmanyam
Nanoscale Adv. 2020, 2, 5591–5599 (Featured on the cover).

Toxicity of Nanomaterials Due to Photochemical Degradation and the Release of Heavy Metal Ions
J. Sobhanan, P. Jones, R. Kohara, S. Sugino, M. Vacha, Ch. Subrahmanyam, Y. Takano, F. Lacy, V. Biju.
Nanoscale 2020, 12, 22049-22058 (Featured on the cover).

Synthesis, Optoelectronic Properties and Applications of Halide Perovskites
L. Chouhan, S. Ghimire, C. Subrahmanyam, T. Miyasaka, V. Biju
Chem. Soc. Rev. 2020, 49, 2869-2885 (Featured on the cover).

Remote Tuning of Bandgap and Emission of Lead Perovskites by Spatially Controlled Halide Exchange Reactions
J. Islam,M. Shahjahan, K. Yuyama, V. Biju
ACS Mater. Lett. 2020, 2, 424-428 (Featured on the cover).

The Optimization of Cancer Photodynamic Therapy by Utilization of a pi-Extended Porphyrin-type Photosensitizer in Combination with MITO-Porter
Satrialdi, R. Munechika, V. Biju, Y. Takano, H. Harashima, Y. Yamada
Chem. Commun. 2020, 56, 1145-1148.

Blinking Beats Bleaching: the Control of Superoxide Generation by Photo‐ionized Perovskite Nanocrystals
L. Chouhan, S. Ghimire, V. Biju
Angew. Chem. Int. Ed. 2019, 58, 4875-4879 (Hot article, Featured on the cover).

Stark Effect and Environment Induced Modulation of Emission in Single Halide Perovskite Nanocrystals
K. Sharma, S. Hirata, V. Biju, M. Vacha
ACS Nano 2019, 13, 624–632.

Mixed-halide Perovskite Synthesis by Chemical Reaction and Crystal Nucleation under an Optical Potential
J. Islam, K. Yuyama, K. Takahashi, T. Nakamura, K. Konishi, V. Biju
NPG Asia Materials 2019, 11, 31.

Photoinduced Photoluminescence Enhancement in Self-Assembled Clusters of Formamidinium Lead Bromide Perovskite Nanocrystals
S. Ghimire, V. C. Nair, C. Muthu, K. Yuyama, M. Vacha, V. Biju
Nanoscale 2019, 11, 9335-9340 (Featured on the cover).

Amplified and Multicolor Emission from Films and Interfacial Layers of Lead Halide Perovskite Nanocrystals
S. Ghimire, L. Chouhan, Y. Takano, K. Takahashi, T. Nakamura, K. Yuyama, V. Biju
ACS Energy Lett. 2019, 4, 133–141.

Blinking Suppression in Highly Excited CdSe/ZnS Quantum Dots by Electron Transfer under Large Positive Gibbs (Free) Energy Change
E. M. Thomas, S. Ghimire, R. Kohara, A. N. Anil, K. Yuyama, Y. Takano, K. G. Thomas, V. Biju
ACS Nano 2018, 12, 9060-9069.

Excitons and Biexciton Dynamics in Single CsPbBr3 Perovskite Quantum Dots
B. Li, H. Huang, G. F. Zhang, C. G. Yang, W. L. Guo, R. Y. Chen, C. B. Qin, Y. Gao, V. Biju, A. L. Rogach, L. T. Xiao, S. T. Jia
J. Phys. Chem. Lett. 2018, 9, 6934-6940.

Relations of exciton dynamics in quantum dots to photoluminescence, lasing, and energy harvesting
S. Ghimire, V. Biju
J. Photochem. Photobiol. C. 2018, 34, 137-151 (Featured on the cover)

Quantum dot–polymer conjugates for stable luminescent displays
S Ghimire, A Sivadas, K Yuyama, Y Takano, R Francis, V Biju
Nanoscale 2018, 10, 13368-13374 (Featured on the cover).

Crystallization of Methylammonium Lead Halide Perovskites by Optical Trapping
K. Yuyama, M. J. Islam, K. Takahashi, T. Nakamura, V. Biju
Angew. Chem. Int. Ed. 2018, 57, 13424-13428 (Hot article, Frontispiece article).

Optical control of mitochondrial reductive reactions in living cells using an electron donor-acceptor linked molecule
Y. Takano, R. Munechika, V. Biju, H. Harashima, H. Imahori, Y. Yamada
Nanoscale 2017, 9, 18690-18698.

Channeling exciton migration into electron transfer in formamidinium lead bromide perovskite nanocrystal/fullerene composites
V. C. Nair, C. Muthu, A. L. Rogach, R. Kohara, V. Biju,
Angew. Chem. Int. Ed. 2017, 56, 1214-1218 (Hot article, Frontispiece article).

Single-particle spectroscopy of I–III–VI semiconductor nanocrystals: spectral diffusion and suppression of blinking by two-color excitation
D. K. Sharma, S. Hirata, L. Bujak, V. Biju, T. Kameyama, M. Kishi, T. Torimoto, M. Vacha
Nanoscale 2016, 8, 13687-13694

Nanoparticles speckled by ready-to-conjugate lanthanide complexes for multimodal imaging
V. Biju, M. Hamada, K. Ono, S. Sugino, T. Ohnishi, E. S. Shibu, S. Yamamura, M. Sawada, S. Nakanishi, Y. Shigeri, S. Wakida
Nanoscale 2015, 7, 148-29-14837 (Featured on the cover).

Auger ionization beats photo-oxidation of semiconductor quantum dots: Extended stability of single-molecule photoluminescence
S. Yamashita, M. Hamada, S. Nakanishi, H. Saito, Y. Nosaka, S. Wakida, V. Biju
Angew. Chem. Int. Ed. 2015, 54, 3892-3896 (Frontispiece article).

Chemical modifications and bioconjugate reactions of nanomaterials for sensing, imaging, drug delivery and therapy
Biju
Chem. Soc. Rev. 2014, 43, 744-764 (Featured on the cover).

Photoluminescence of CdSe and CdSe/ZnS quantum dots: Modifications for making the invisible visible at the ensemble and single-molecule levels
E. Shibu, M. Hamada, S. Nakanishi, S. Wakida, V. Biju
Coord. Chem. Rev. 2014, 263, 2-12.

Singlet-oxygen-sensitizing near-infrared-fluorescent multimodal nanoparticles
E. Shibu, S. Sugino, K. Ono, H. Saito, S. Yamamura, M. Sawada, Y. Nosaka, V. Biju
Angew. Chem. Int. Ed. 2013, 52, 10559-10563.

Photouncaging nanoparticles for MRI and fluorescence imaging in vitro and in vivo
E. Shibu, K. Ono, S. Sugino, A. Nishioka, A. Yasuda, Y. Shigeri, S. Wakida, M. Sawada, V. Biju
ACS Nano 2013, 7, 9851-9859.

Impairments of cells and genomic DNA by environmentally transformed engineered nanomaterials
P. Jones, S. Sugino, S. Yamamura, F. Lacy, V. Biju
Nanoscale 2013, 5, 9511-9516 (Featured on the cover).

Nanomaterials formulations for photothermal and photodynamic therapy of cancer
E. Shibu, M. Hamada, N. Murase, V. Biju
J. Photochem. Photobiol. C 2013, 15, 53-72.

FRET from quantum dots to photodecompose undesired acceptors and report the condensation and decondensation of plasmid DNA
V. Biju, A. Anas, H. Akita, E. S. Shibu, T. Itoh, H. Harashima, M. Ishikawa
ACS Nano 2012, 6, 3776-3788.

Fullerene-shelled quantum dots supramolecular nanoparticles for solar energy harvesting
E. Shibu, A. Sonoda, W. Tao, Q. Feng, A. Furube, S. Masuo, L. Wang, N. Tamai, M. Ishikawa, V. Biju
ACS Nano 2012, 6, 1601-1608.

Quantitative analysis of condensation/decondensation status of pDNA in the nuclear sub-domains by QD-FRET
S. M. Shaheen, H. Akita, A. Yamashita, R. Katoono, N. Yui, V. Biju, M. Ishikawa, H. Harashima
Nucl. Acid. Res. 2011, 39, E48-U108.

Delivering quantum dots to cells: bioconjugated quantum dots for targeted and nonspecific extracellular and intracellular imaging
V. Biju, T. Itoh, M. Ishikawa
Chem. Soc. Rev. 2010, 39, 3031-3056.

Blinking suppression in CdSe/ZnS single quantum dots by TiO2 nanoparticles
M. Hamada, S. Nakanishi, T. Itoh, M. Ishikawa, V. Biju
ACS Nano 2010, 4, 4445-4454.

Bioconjugated quantum dots for cancer research: Present status, prospects and remaining issues
V. Biju, S. Mundayoor, A. Anas, M. Ishikawa
Biotechnol. Adv. 2009, 28, 199-213.

Clathrin-mediated endocytosis of quantum dot−peptide conjugates in living cells
A. Anas, T. Okuda, N. Kawashima, K. Nakayama, T. Itoh, M. Ishikawa, V. Biju
ACS Nano 2009, 3, 2419-2429.

Intermittent single-molecule interfacial electron transfer dynamics
V. Biju, M. Micic, D. Hu, H. P. Lu
J. Am. Chem. Soc. 2004, 126, 9374-9381.

RECENT PUBLICATIONS

Toxicity of Nanomaterials Due to Photochemical Degradation and the Release of Heavy Metal Ions

J. Sobhanan, P. Jones, R. Kohara, S. Sugino, M. Vacha, Ch. Subrahmanyam, Y. Takano, F. Lacy, V. Biju (Equal contribution)

Nanoscale 2020, DOI: 10.1039/D0NR03957H

Synthesis, Optoelectronic Properties and Applications of Halide Perovskites

L. Chouhan, S. Ghimire, C. Subrahmanyam, T. Miyasaka, V. Biju

Chem. Soc. Rev. 2020, 49, 2869-2885 (Cover page article); doi.org/10.1039/C9CS00848A

Remote Tuning of Bandgap and Emission of Lead Perovskites by Spatially Controlled Halide Exchange Reactions

M. J. Islam,M. Shahjahan, K. Yuyama, V. Biju

ACS Mater. Lett. 2020, 2, 424-428 (Cover page article)

https://pubs.acs.org/doi/10.1021/acsmaterialslett.0c00036

Nonradiative Energy Transfer through Distributed Bands in Piezochemically Synthesized Cesium and Formamidinium Lead Halide Perovskites

S. B. Bhagyalakshmi, S. Ghimire, K. Takahashi, K. Yuyama, Y. Takano, T. Nakamura, V. Biju

Chem. Eur. J. 2020, 26, 2133-2137 (Hot paper & Cover page article).

https://onlinelibrary.wiley.com/doi/epdf/10.1002/chem.201904300

Photoinduced Betaine Generation for Efficient Photothermal Energy Conversion

D. Sasikumar, Y. Takano, V. Biju

Chem. Eur. J. 2020, 26, 2060-2066.

https://onlinelibrary.wiley.com/toc/15213765/2020/26/9

The Optimization of Cancer Photodynamic Therapy by Utilization of a pi-Extended Porphyrin-type Photosensitizer in Combination with MITO-Porter

Satrialdi, R. Munechika, V. Biju, Y. Takano, H. Harashima, Y. Yamada

Chem. Commun. 2020, 56, 1145-1148.

https://pubs.rsc.org/en/content/articlepdf/2020/cc/c9cc08563g

Photon Recycling by Energy Transfer in Piezochemically Synthesized and Close-Packed Methylammonium Lead Halide Perovskites

S. Ghimire, K. Takahashi, Y. Takano, T. Nakamura, V. Biju

J. Phys. Chem. C. 2019, 123, 27752-2775 (Cover page article)

https://pubs.acs.org/doi/abs/10.1021/acs.jpcc.9b07003

Extinction of Antimicrobial Resistant Pathogens Using Silver Embedded Silica Nanoparticles and an Efflux Pump Blocker

J. Jose, A. Anas, B. Jose, A. B. Puthirath, S. Athiyanathil, C. Jasmin, M. R. Anantharaman, S. Nair, Ch. Subrahmanyam, V. Biju

ACS Appl. Bio Mater. 2019, 2, 4681-4686.
https://pubs.acs.org/doi/abs/10.1021/acsabm.9b00614

Mixed-halide Perovskite Synthesis by Chemical Reaction and Crystal Nucleation under an Optical Potential

M. J. Islam, K. Yuyama, K. Takahashi, T. Nakamura, K. Konishi, V. Biju

NPG Asia Materials 2019, 11, 31.

Photoinduced Photoluminescence Enhancement in Self-Assembled Clusters of Formamidinium Lead Bromide Perovskite Nanocrystals

S. Ghimire, V. C. Nair, C. Muthu, K. Yuyama, M. Vacha, V. Biju

Nanoscale 201911, 9335-9340 (Cover page article).

https://10.1039/C8NR10082A

Blinking Beats Bleaching: the Control of Superoxide Generation by Photo‐ionized Perovskite Nanocrystals

L. Chouhan, S. Ghimire, V. Biju

Angew. Chem. Int. Ed. 2019, 58, 4875-4879 (Hot paper & Cover page article).

https://doi.org/10.1002/anie.201900061

Stark Effect and Environment Induced Modulation of Emission in Single Halide Perovskite Nanocrystals

D. K. Sharma, S. Hirata, V. Biju, M. Vacha

ACS Nano 2019, 13, 624–632.

https://pubs.acs.org/doi/abs/10.1021/acsnano.8b07677

Kinetics of Singlet oxygen Sensing using 9-Substituted Anthracene Derivatives 

D. Sasikumar, R. Kohara, Y. Takano, K. Yuyama, V. Biju

J. Chem. Sci. 2019, 131, 5.

https://link.springer.com/article/10.1007/s12039-018-1578-1

Amplified and Multicolor Emission from Films and Interfacial Layers of Lead Halide Perovskite Nanocrystals

S. Ghimire, L. Chouhan, Y. Takano, K. Takahashi, T. Nakamura, K. Yuyama, V. Biju

ACS Energy Lett. 20194, 133–141.

https://pubs.acs.org/doi/abs/10.1021/acsenergylett.8b01916

In Situ Reflection Imaging and Microspectroscopic Study on Three-dimensional Crystal Growth of L-Phenylalanine under Laser Trapping

J. J. K. Chen, K. Yuyama, T. Sugiyama, H. Masuhara
Appl. Phys. Exp. 2019, 12, 112008.

https://iopscience.iop.org/article/10.7567/1882-0786/ab4a9e

Phase Transfer Reaction for the Preparation of Stable Polymer-Quantum Dot Conjugates

G. P. Gopalan, A. N. Anil, S. Ghimire, N. Joy, K. Yuyama, V. Biju, R. R Francis

J. Photochem. Photobiol. A: Chem. 2019, 371, 9791–9792.

https://www.sciencedirect.com/science/article/pii/S101060301830947X

Excitons and Biexciton Dynamics in Single CsPbBr3 Perovskite Quantum Dots

B. Li, H. Huang, G. Zhang, C. Yang, W. Guo, R. Chen, C. Qin, Y. Gao, V. Biju, A. L. Rogach, L. Xiao, S. Jia

J. Phys. Chem. Lett. 2018, 9, 6934-6940.

https://pubs.acs.org/doi/abs/10.1021/acs.jpclett.8b03098

Blinking Suppression in Highly Excited CdSe/ZnS Quantum Dots by Electron Transfer under Large Positive Gibbs (Free) Energy Change

E. M. Thomas, S. Ghimire, R. Kohara, A. N. Anil, K. Yuyama, Y. Takano, K. G. Thomas, V. Biju

ACS Nano 2018, 12, 9060-9069.(†Equal authorship)

https://pubs.acs.org/doi/abs/10.1021/acsnano.8b03010

Crystallization of Methylammonium Lead Halide Perovskites by Optical Trapping

K. Yuyama, M. J. Islam, K. Takahashi, T. Nakamura, V. Biju

Angew. Chem. Int. Ed. 2018, 57, 13424-13428 (Hot paper and frontispiece paper).

https://onlinelibrary.wiley.com/doi/epdf/10.1002/anie.201806079

Relations of Exciton Dynamics in Quantum Dots to Photoluminescence, Lasing, and Energy Harvesting

S. Ghimire, V. Biju

Photochem. Photobiol. C: Photochem. Rev. 2018, 34, 137-151.(Cover page article)

https://doi.org/10.1016/j.jphotochemrev.2018.01.004

Quantum Dot–Polymer Conjugates for Stable Luminescent Displays

S. Ghimire, A. Sivadas, K. Yuyama, Y. Takano, R. Francis, V. Biju

Nanoscale 201810, 13368-13374 (Cover page article).

https://pubs.rsc.org/en/content/articlepdf/2018/nr/c8nr01501e

Development of Technologies for Sensing Ozone in Ambient Air

M. Ando, V. Biju, Y. Shigeri

Anal. Sci. 2018, 34, 263-271.

https://www.jstage.jst.go.jp/article/analsci/34/3/34_263/_pdf/-char/ja

Quantum Dot-Peptide Nanoassembly on Mesoporous Silica Nanoparticle for Biosensing

S. S. Pillai, H. Yukawa, D. Onoshima, V. Biju, Y. Baba
Nano Hybrids and Composites 2018, 19, 55-72.

https://www.scientific.net/NHC.19.55

Blue‐Emitting Electron‐Donor/Acceptor Dyads for Naked‐Eye Fluorescence Detection of Singlet Oxygen

Kohara, K. Yuyama, Y. Shigeri, V. Biju

ChemPhotoChem 2017, 1, 299-303 (Cover page article).

https://doi.org/10.1002/cptc.201700046

Channeling Exciton Migration into Electron Transfer in Formamidinium Lead Bromide Perovskite Nanocrystal/Fullerene Composites

V. C. Nair, C. Muthu, A. L. Rogach, R. Kohara, V. Biju

Angew. Chem. Int. Ed. 2017, 56, 1214-1218 (Hot article and frontispiece article).

https://doi.org/10.1002/anie.201610070

Influence of Zn on the Photoluminescence of Colloidal (AgIn) x Zn 2 (1− x) S 2 Nanocrystals

D. K. Sharma, S. Hirata, L. Bujak, V. Biju, T. Kameyama, M. Kishi, T. Torimoto, M. Vacha

Phys. Chem. Chem. Phys. 2017, 19, 3963-3969.

https://pubs.rsc.org/en/content/articlepdf/2017/cp/c6cp07550a

Forster Resonance Energy Transfer Mediated Photoluminescence Quenching in Stoichiometrically Assembled CdSe/ZnS Quantum Dot-Peptide Labeled Black Hole Quencher Conjugates for Matrix Metalloproteinase-2 Sensing

S. S. Pillai, H. Yukawa, D. Onoshima, V. Biju, Y. Baba

Anal. Sci. 2017, 33, 137-142.

https://www.jstage.jst.go.jp/article/analsci/33/2/33_137/_pdf/-char/ja

In vivo ROS Production and Use of Oxidative Stress-derived Biomarkers to Detect the Onset of Diseases such as Alzheimer’s Disease, Parkinson’s Disease, and Diabetes

A. Umeno,V. Biju, Y. Yoshida

Free Rad. Res. 2017, 51, 413-427.

https://www.tandfonline.com/doi/full/10.1080/10715762.2017.1315114

Reversible Photoluminescence Sensing of Gaseous Alkylamines using CdSe-Based Quantum Dots

M. Ando, T. Kamimura, K. Uegaki, V. Biju, J. T. D. Ty, Y. Shigeri

Sens. Act. B: Chem. 2017, 246, 1074-1079.

https://www.sciencedirect.com/science/article/pii/S0925400517300655

Sensing of Ozone Based on Its Quenching Effect on the Photoluminescence of CdSe-based Core-Shell Quantum Dots

M. Ando, T. Kamimura, K. Uegaki, V. Biju, Y. Shigeri

Microchim Acta 2016, 183, 3019–3024.

Single-Particle Spectroscopy of I–Iii–Vi Semiconductor Nanocrystals: Spectral Diffusion and Suppression of Blinking by Two-Color Excitation

D. K. Sharma, S. Hirata, L. Bujak, V. Biju, T. Kameyama, M. Kishi, T. Torimotoc, M. Vacha

Nanoscale, 2016, 8, 13687-13694.

https://pubs.rsc.org/en/content/articlepdf/2016/nr/c6nr03950b

Selected Publications (V. Biju)

Blinking Suppression in Highly Excited CdSe/ZnS Quantum Dots by Electron Transfer under Large Positive Gibbs (Free) Energy Change

E. M. Thomas, S. Ghimire, R. Kohara, A. N. Anil, K. Yuyama, Y. Takano, K. G. Thomas, V. Biju

ACS Nano 2018, 12, 9060-9069.

Crystallization of Methylammonium Lead Halide Perovskites by Optical Trapping

K. Yuyama, M. J. Islam, K. Takahashi, T. Nakamura, V. Biju

Angew. Chem. Int. Ed. 2018, 57, 13424–13428. (Frontispiece Article)

Relations of exciton dynamics in quantum dots to photoluminescence, lasing, and energy harvesting

S. Ghimire, V. Biju

J. Photochem. Photobiol. C: Photochem. Rev. 2018, 34, 137-151. (Featured on the cover)

Quantum dot–polymer conjugates for stable luminescent displays

S. Ghimire, A. Sivadas, K. Yuyama, Y. Takano, R. Francis, V. Biju

Nanoscale 201810, 13368-13374. (Featured on the cover)

Blue‐Emitting Electron‐Donor/Acceptor Dyads for Naked‐Eye Fluorescence Detection of Singlet Oxygen

R. Kohara, K. Yuyama, Y. Shigeri, V. Biju

ChemPhotoChem 2017, 1, 299-303. (Featured on the cover)

Channeling Exciton Migration into Electron Transfer in Formamidinium Lead Bromide Perovskite Nanocrystal/Fullerene Composites

V. C. Nair, C. Muthu, A. L. Rogach, R. Kohara, V. Biju

Angew. Chem. Int. Ed. 2017, 56, 1214-1218. (Frontispiece and hot article)

Auger ionization beats photo-oxidation of semiconductor quantum dots: Extended stability of single-molecule photoluminescence

Y. Yamashita, M. Hamada, S. Nakanishi, H. Saito, Y. Nosaka, S. Wakida, V. Biju

Angew. Chem. Int. Ed. 2015, 54, 3892-3896. (Frontispiece article)

Nanoparticles speckled by ready-to-conjugate lanthanide complexes for multimodal imaging

V. Biju, M. Hamada, K. Ono, S. Sugino, T. Ohnishi, E. S. Shibu, S. Yamamura, S. Sawada, S. Nakanishi, S. Shigeri, S. Wakida

Nanoscale 2015, 7, 14829-14837. (Featured on the cover)

Chemical modifications and bioconjugate reactions of nanomaterials for sensing, imaging, drug delivery and therapy

V. Biju

Chem. Soc. Rev. 2014, 43, 744-764. (Featured on the cover)

In situ photochemical surface passivation of CdSe/ZnS quantum dots for quantitative light emission and enhanced photocurrent response in solar cells

M. Hamada, N. Takenokoshi, K. Motozaki, Q. Feng, N. Murase, S. Wakida, S. Nakanishi, V. Biju*

J. Phys. Chem. C. 2014, 118, 2178-2186. (Featured on the cover)

Photoluminescence of CdSe and CdSe/ZnS quantum dots: Modifications for making the invisible visible at ensemble and single-molecule levels

E. S. Shibu, M. Hamada, S. Nakanishi, S. Wakida, V. Biju

Coord. Chem. Rev. 2014, 263, 2-12.

 

Singlet-oxygen-sensitizing near-infrared-fluorescent multimodal nanoparticles

E. S. Shibu, S. Sugino, K. Ono, H. Saito, Y. Yamamura, S. Sawada, Y. Nosaka, V. Biju

Angew. Chem. Int. Ed. 2013, 52, 10559-10563.

 

Photouncaging nanoparticles for MRI and fluorescence imaging in vitro and in vivo

E. S. Shibu, K. Ono, S. Sugino, A. Nishioka, A. Yasuda, Y. Shigeri, S. Wakida, M. Sawada, V. Biju*

ACS Nano 2013, 7, 9851-9859.

 

Impairments of cells and genomic DNA by environmentally transformed engineered nanomaterials

P. Jones, S. Sugino, Y. Yamamura, F. Lacy, V. Biju*

Nanoscale 2013, 5, 9511-9516. (Featured on the cover)

Nanomaterials formulations for photothermal and photodynamic therapy of cancer

E. S. Shibu, M. Hamada, N. Murase, V. Biju*

J. Photochem. Photobiol. C: Photochem. Rev. 2013, 15, 53-72.

 

FRET from quantum dots to photodecompose undesired acceptors and report the condensation and decondensation of plasmid DNA

V. Biju,* A. Anas, H. Akita, E. S. Shibu, T. Itoh, H. Harashima, M. Ishikawa, M.

ACS Nano 2012, 6, 3776-3788.

 

Fullerene-shelled quantum dots supramolecular nanoparticles for solar energy harvesting

E. S. Shibu, A. Sonoda, W, Tao, Q. Feng, A. Furube, S. Masuo, L. Wang, N. Tamai, M. Ishikawa, V. Biju*

ACS Nano 2012, 6, 1601-1608.

 

Delivering quantum dots to cells: bioconjugated quantum dots for targeted and nonspecific extracellular and intracellular imaging

V. Biju,* T. Itoh, M. Ishikawa

Chem. Soc. Rev. 2010, 39, 3031-3056.

 

Blinking suppression in CdSe/ZnS single quantum dots by TiO2 nanoparticles

M. Hamada, S. Nakanishi, T. Itoh, M. Ishikawa, V. Biju*

ACS Nano 2010, 4, 4445-4454.

 

Reversible dimerization of EGFR revealed by single-molecule fluorescence imaging using quantum dots

N. Kawashima, K. Nakayama, K. Itoh, T. Itoh, M. Ishikawa, V. Biju*

Chem. Eur. J. 2010, 16, 1186-1192. (Featured on the cover)

Bioconjugated quantum dots for cancer research: Present status, prospects and remaining issues

V. Biju,* S. Mundayoor, A. Anas, M. Ishikawa

Biotechnol. Adv. 2010, 28, 199-213.

Clathrin-mediated endocytosis of quantum dot−peptide conjugates in living cells

A. Anas, T. Okuda, N. Kawashima, K. Nakayama, T. Itoh, M. Ishikawa, V. Biju*

ACS Nano 2009, 3, 2419-2429. (Featured Science and Technology News in C&EN)

Photosensitized breakage and damage of DNA by CdSe-ZnS quantum dots

A. Anas, H. Akita, K. Harashima, T. Itoh, M. Ishikawa, V. Biju*

J. Phys. Chem. B 2008, 112, 10005-10011. (Featured on the cover)

Relations between dewetting of polymer thin films and phase-separation of encompassed quantum dots

R. Kanemoto, A. Anas, Y. Matsumoto, R. Ueji, T. Itoh, Y. Baba, S. Nakanishi, M. Ishikawa, V. Biju*

J. Phys. Chem. B 2008, 112, 9312-9319. (Featured on the cover)

Photoluminescence quenching and intensity fluctuations of CdSe-ZnS quantum dots on an Ag nanoparticle film

Y. Matsumoto, R. Kanemoto, T. Itoh, S. Nakanishi, M. Ishikawa, V. Biju*

J. Phys. Chem. B 2008, 112, 1345-1350. (Featured on the cover)

Photoinduced photoluminescence variations of CdSe quantum dots in polymer solutions

V. Biju,* R. Kanemoto, Y. Matsumoto, S. Ishii, T. Itoh, S. Nakanishi, Y. Baba, M. Ishikawa

J. Phys. Chem. C 2007, 111, 7924-7932. (Featured on the cover)

Temperature-sensitive photoluminescence of CdSe quantum dot clusters

V. Biju,* Y. Makita, A. Sonoda, Y. Baba, H. Yokoyama, M. Ishikawa

J. Phys. Chem. B 2005, 109, 13899-13905. (Featured on the cover)

Intermittent single-molecule interfacial electron transfer dynamics

V. Biju, M. Micic, D. Hu, H. P. Lu*

J. Am. Chem. Soc. 2004, 126, 9374-9381.

Previous Publications (Y. Takano)

Original paper:

1.     Optical Control of Neuronal Firing via Photoinduced Electron Transfer in Donor–Acceptor Conjugates (Open access)

Y. Takano, T. Numata, K. Fujishima, K. Miyake, K. Nakao, W. D. Grove, R. Inoue, M. Kengaku, S. Sakaki, Y. Mori, T. Murakami, and H. Imahori,  Chem. Sci., 2016, 7, 3331-3337.

2.     Molecular Location Sensing Approach by Anisotropic Magnetism of an Endohedral Metallofullerene*

Y. Takano, R. Tashita, M. Suzuki, S. Nagase, H. Imahori and T. Akasaka, J. Am. Chem. Soc., 2016, 138, 8000-8006.

*Highlighted by “Chem-Station”   http://www.chem-station.com/blog/2016/11/fullereneradar.html

3.     The Unanticipated Dimerization of Ce@C2v(9)-C82 upon Co-crystallization with Ni(octaethylporphyrin) and Comparison with Monomeric M@C2v(9)-C82 (M = La, Sc, and Y)

M. Suzuki, M. Yamada, Y. Maeda, S. Sato, Y. Takano, F. Uhlik, Z. Slanina, Y. F. Lian, X. Lu, S. Nagase, M. M. Olmstead, A. L. Balch and T. Akasaka, Chem. Eur. J., 2016, 22, 18115-18122.

4.     Unprecedented Chemical Reactivity of a Paramagnetic Endohedral Metallofullerene La@Cs-C82 that Leads Hydrogen Addition in the 1,3-Dipolar Cycloaddition Reaction

Y. Takano, Z. Slanina, J. Mateos, T. Tsuchiya, H. Kurihara, F. Uhlik, M. A. Herranz, N. Martin, S. Nagase and T. Akasaka, J. Am. Chem. Soc., 2014, 136, 17537-17546.

5.     Thermodynamically Stable [4+2] Cycloadducts of Lanthanum-encapsulated Endohedral Metallofullerenes (Open access)

Y. Takano, Y. Nagashima, M. A. Herranz, N. Martin and T. Akasaka, Beilstein J. Org. Chem., 2014, 10, 714-721.

6.     Slow Charge Recombination and Enhanced Photoelectrochemical Properties of Diazaporphyrin-Fullerene Linked Dyad

M. Yamamoto, Y. Takano, Y. Matano, K. Stranius, N. V. Tkachenko, H. Lemmetyinen and H. Imahori, J. Phys. Chem. C, 2014, 118, 1808-1820.

7.     Intramolecular versus Intermolecular Electronic Interactions between [5,6]-Open and [6,6]-Closed C60 Adducts with exTTF

Y. Takano, C. Schubert, N. Mizorogi, L. Feng, A. Iwano, M. Katayama, M. A. Herranz, D. M. Guldi, N. Martin, S. Nagase and T. Akasaka, Chem. Sci., 2013, 4, 3166-3171.

8.     Electrochemical and Magnetic Properties of a Surface-Grafted Novel Endohedral Metallofullerene Derivative (Open access)

N. Crivillers, Y. Takano, Y. Matsumoto, J. Casado-Montenegro, M. Mas-Torrent, C. Rovira, T. Akasaka and J. Veciana, Chem. Commun., 2013, 49, 8145-8147.

9.     An Endohedral Metallofullerene as a Pure Electron Donor: Intramolecular Electron Transfer in Donor Acceptor Conjugates of La2@C80 and 11,11,12,12-Tetracyano-9,10-anthra-p-quinodimethane (TCAQ)

Y. Takano, S. Obuchi, N. Mizorogi, R. Garcia, M. A. Herranz, M. Rudolf, D. M. Guldi, N. Martin, S. Nagase and T. Akasaka, J. Am. Chem. Soc., 2012, 134, 19401-19408.

10.  Stabilizing Ion and Radical Ion Pair States in a Paramagnetic Endohedral Metallofullerene/pi-Extended Tetrathiafulvalene Conjugate

Y. Takano, S. Obuchi, N. Mizorogi, R. Garcia, M. A. Herranz, M. Rudolf, S. Wolfrum, D. M. Guldi, N. Martin, S. Nagase and T. Akasaka,  J. Am. Chem. Soc., 2012, 134, 16103-16106.

11.  Utilization of Photoinduced Charge-Separated State of Donor-Acceptor-Linked Molecules for Regulation of Cell Membrane Potential and Ion Transport

T. Numata, T. Murakami, F. Kawashima, N. Morone, J. E. Heuser, Y. Takano, K. Ohkubo, S. Fukuzumi, Y. Mori and H. Imahori, J. Am. Chem. Soc., 2012, 134, 6092-6095.

12.  Effects of Dihydronaphthyl-based [60]Fullerene Bisadduct Regioisomers on Polymer Solar Cell Performance

S. Kitaura, K. Kurotobi, M. Sato, Y. Takano, T. Umeyama and H. Imahori, Chem. Commun., 2012, 48, 8550-8552.

13.  Enantioselective Synthesis of Endohedral Metallofullerenes

K. Sawai, Y. Takano, M. Izquierdo, S. Filippone, N. Martin, Z. Slanina, N. Mizorogi, M. Waelchli, T. Tsuchiya, T. Akasaka and S. Nagase, J. Am. Chem. Soc., 2011, 133, 17746-17752.

14.  Introduction of Azetidinimine Skeleton on C60

Ueda, H. Nikawa, Y. Takano, M. O. Ishitsuka, T. Tsuchiya and T. Akasaka, Heteroat. Chem., 2011, 22, 426-431.

15.  Donor-Acceptor Conjugates of Lanthanum Endohedral Metallofullerene and pi-Extended Tetrathiafulvalene

Y. Takano, M. A. Herranz, N. Martin, S. G. Radhakrishnan, D. M. Guldi, T. Tsuchiya, S. Nagase and T. Akasaka, J. Am. Chem. Soc., 2010, 132, 8048.

16.  Retro-Reaction of Singly Bonded La@C82 Derivatives

Y. Takano, M. O. Ishitsuka, T. Tsuchiya, T. Akasaka, T. Kato and S. Nagase, Chem. Commun., 2010, 46, 8035-8036.

17.  Electron Donor-Acceptor Interactions in Regioselectively Synthesized exTTF2-C70(CF3)10 Dyads

Y. Takano, M. A. Herranz, N. Martin, G. D. Rojas, D. M. Guldi, I. E. Kareev, S. H. Strauss, O. V. Boltalina, T. Tsuchiya and T. Akasaka, Chem. -Eur J., 2010, 16, 5343-5353.

18.  Anisotropic Magnetic Behavior of Anionic Ce@C82 Carbene Adducts

Y. Takano, M. Aoyagi, M. Yamada, H. Nikawa, Z. Slanina, N. Mizorogi, M. O. Ishitsuka, T. Tsuchiya, Y. Maeda, T. Akasaka, T. Kato and S. Nagase, J. Am. Chem. Soc., 2009, 131, 9340-9346.

19.  Efficient Regioselective [4+2] Cycloaddition of o-Quinodimethane to C70(CF3)10

Y. Takano, M. A. Herranz, I. E. Kareev, S. H. Strauss, O. V. Boltalina, T. Akasaka and N. Martin, J. Org. Chem., 2009, 74, 6902-6905.

20.  Radical Coupling Reaction of Paramagnetic Endohedral Metallofullerene La@C82

Y. Takano, A. Yomogida, H. Nikawa, M. Yamada, T. Wakahara, T. Tsuchiya, M. O. Ishitsuka, Y. Maeda, T. Akasaka, T. Kato, Z. Slanina, N. Mizorogi and S. Nagase, J. Am. Chem. Soc., 2008, 130, 16224-16230.

21.  Nanorods of Endohedral Metallofullerene Derivative

T. Tsuchiya, R. Kumashiro, K. Tanigaki, Y. Matsunaga, M. O. Ishitsuka, T. Wakahara, Y. Maeda, Y. Takano, M. Aoyagi, T. Akasaka, M. T. H. Liu, T. Kato, K. Suenaga, J. S. Jeong, S. Iijima, F. Kimura, T. Kimura and S. Nagase, J. Am. Chem. Soc., 2008, 130, 450-451.

22.  Simple Purification and Selective Enrichment of Metallic SWCNTs Produced using the Arc-Discharge Method

Y. Maeda, Y. Takano, A. Sagara, M. Hashimoto, M. Kanda, S. I. Kimura, Y. Lian, T. Nakahodo, T. Tsuchiya, T. Wakahara, T. Akasaka, T. Hasegawa, S. Kazaoui, N. Minami, J. Lu and S. Nagase, Carbon, 2008, 46, 1563-1569.

Review paper:

1.     Intramolecular Electron Transfers in Donor/Acceptor Linked Molecules Based on Endohedral Lanthanide Metallofullerenes

Y. Takano, Fuller. Nanotub. Car. N., 2014, 22, 243-249.

2.     Rates and energetics of intramolecular electron transfer processes in conjugated metallofullerenes

Schubert, M. Rudolf, D. M. Guldi, Y. Takano, N. Mizorogi, M. A. Herranz, N. Martin, S. Nagase and T. Akasaka, Philos. T. R. Soc. A, 2013, 371, 20120490 .

3.     New Vistas in fullerene Chemistry: Organosulfur Compounds expand the Performance of Carbon Nanomaterials

T. Akasaka, T. Tsuchiya, L. Feng, Y. Takano and S. Nagase, Phosphorus Sulfur, 2013, 188, 317-321.

4.     Self-assembling porphyrins and phthalocyanines for photoinduced charge separation and charge transport

H. Imahori, T. Umeyama, K. Kurotobi and Y. Takano, Chem. Commun., 2012, 48, 4032-4045.

5.     Current Progress on the Chemical Functionalization and Supramolecular Chemistry of M@C82

Y. Maeda, T. Tsuchiya, X. Lu, Y. Takano, T. Akasaka and S. Nagase, Nanoscale, 2011, 3, 2421-2429.

6.     Organosulfur-Based Fullerene Materials

T. Nakahodo, M. O. Ishitsuka, Y. Takano, T. Tsuchiya, T. Akasaka, M. A. Herranz, N. Martin, D. M. Guldi and S. Nagase, Phosphorus Sulfur, 2011, 186, 1308-1311.

Book chapter:

1.     Endohedral Metallofullerenes: From Chemical Reactivity to Material Performance

M. Yamada, S. Sato, Y. Takano, L. Feng, S. Nagase and T. Akasaka, Chemical Science of pi-Electron Systems Part II. Curved pi-Electron Systems, ed. T. Akasaka, A. Osuka, S. Fukuzumi, H. Kandori and Y. Aso, Springer, Berlin, Germany, 2015, ch. 10.

2.     Fundamental and Applied Aspects of Endohedral Metallofullerenes as Promising Carbon Nanomaterials

M. Yamada, X. Lu, L. Feng, S. Sato, Y. Takano, S. Nagase and T. Akasaka, Organic Nanomaterials -Synthesis, Characterization, and Device Applications-, ed. T. Torres and G. Bottari, Wiley, London, U.K., 2013, ch. 12, pp. 241-258.

 

Research

The main research subjects we are focusing on are

  • Creation of novel fluorescent nanomaterials and organic molecules for photonics

  • Control of charge carrier dynamics and fluorescence blinking in nanomaterials

  • Optical detection and control of biomolecular functioning in living cells

  • Manipulation of molecules and nanomaterials using laser tweezers

In these research subjects, we employ steady-state and time-resolved fluorescence spectroscopy, single molecule fluorescence microspectroscopy, and laser trapping microspectroscopy.

   Please see our publication list also (click here to link)

Creation of novel nanomaterials and organic molecules for photonics

We develop luminescent semiconductor nanomaterials which have unique electronic and optical properties. These include lead halide perovskites and chalcogenide quantum dots.

We investigate the charge carrier, fluorescence and electron transfer dynamics of the above nanomaterials at the ensemble and single-molecule levels.

We develop molecular sensors of oxidative stress and biological electron transfer reactions. These sensors include organic electron donor-acceptor dyads.

We develop biomolecular assemblies and perovskite crystals by optical trapping.

Control of charge carrier dynamics and fluorescence blinking in nanomaterials

Groundbreaking advances in photo-voltaic and optoelectronic technologies depend mostly on a realization of novel materials having unique optical properties.

We focus a part of our effort on the design and development of novel photo-active nanomaterials in one, two, and three dimensions, with an emphasis on precisely controlling the optical activity.

Organic and inorganic molecules are our raw materials and wet thermal chemistry and photochemistry are our tools. By optimally controlling the size, shape, and composition of nanomaterials, we generate unique fluorescence, phosphorescence and photothermal properties.

Subsequently, such nanomaterials will be applied to selected problems in biosensing, bioimaging, energy harvesting, and environmental remediation.

 

Chemical syntheses for detection and optical control of biomolecular functioning in living cells

 Optical control (light control) on the matter is a powerful and promising method because it can achieve precise spatiotemporal control (<μm, <nsec scale).

   Our group develops photo-functional organic molecules and nanomaterials for efficient control and detection of living cellular activities.

This technology will contribute to developing novel bio prove for chemical biology and phototherapy for medicine, including emerging cancer phototherapy.

   For this purpose, we design, synthesize and investigate new molecules and nanomaterials which possess controllable and efficient photoexcited states.

Bio-Nano Interface

Exploration of the interface between biology and nanoscience not only resolves fundamental problems in laboratory life science but also reforms our lives.

Our laboratory is interested in developing novel nanobioconjugates, and molecular probes, and applying the conjugates to pinpoint the functioning of biomolecules at the single-molecule and single-cell levels.