Research

The main research subjects we are focusing on are

  • Creation of novel fluorescent nanomaterials and organic molecules for photonics

  • Control of charge carrier dynamics and fluorescence blinking in nanomaterials

  • Optical detection and control of biomolecular functioning in living cells

  • Manipulation of molecules and nanomaterials using laser tweezers

In these research subjects, we employ steady-state and time-resolved fluorescence spectroscopy, single molecule fluorescence microspectroscopy, and laser trapping microspectroscopy.

   Please see our publication list also (click here to link)

Creation of novel nanomaterials and organic molecules for photonics

We develop luminescent semiconductor nanomaterials which have unique electronic and optical properties. These include lead halide perovskites and chalcogenide quantum dots.

We investigate the charge carrier, fluorescence and electron transfer dynamics of the above nanomaterials at the ensemble and single-molecule levels.

We develop molecular sensors of oxidative stress and biological electron transfer reactions. These sensors include organic electron donor-acceptor dyads.

We develop biomolecular assemblies and perovskite crystals by optical trapping.

Control of charge carrier dynamics and fluorescence blinking in nanomaterials

Groundbreaking advances in photo-voltaic and optoelectronic technologies depend mostly on a realization of novel materials having unique optical properties.

We focus a part of our effort on the design and development of novel photo-active nanomaterials in one, two, and three dimensions, with an emphasis on precisely controlling the optical activity.

Organic and inorganic molecules are our raw materials and wet thermal chemistry and photochemistry are our tools. By optimally controlling the size, shape, and composition of nanomaterials, we generate unique fluorescence, phosphorescence and photothermal properties.

Subsequently, such nanomaterials will be applied to selected problems in biosensing, bioimaging, energy harvesting, and environmental remediation.

 

Chemical syntheses for detection and optical control of biomolecular functioning in living cells

 Optical control (light control) on the matter is a powerful and promising method because it can achieve precise spatiotemporal control (<μm, <nsec scale).

   Our group develops photo-functional organic molecules and nanomaterials for efficient control and detection of living cellular activities.

This technology will contribute to developing novel bio prove for chemical biology and phototherapy for medicine, including emerging cancer phototherapy.

   For this purpose, we design, synthesize and investigate new molecules and nanomaterials which possess controllable and efficient photoexcited states.

Bio-Nano Interface

Exploration of the interface between biology and nanoscience not only resolves fundamental problems in laboratory life science but also reforms our lives.

Our laboratory is interested in developing novel nanobioconjugates, and molecular probes, and applying the conjugates to pinpoint the functioning of biomolecules at the single-molecule and single-cell levels.